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BACKGROUND: Vbeam® and Cynergy® are 595 nm pulsed dye laser(PDL) equipment options, both extensively used in clinical treatment of port-wine stain (PWS). However, there has been no study conducted of the differences in PWS therapeutic outcomes across both devices.OBJECTIVE: To compare of the efficacy and safety of Vbeam and Cynergy equipment in the treatment of PWS.METHOD: Twenty-two PWS patients were included this study and were treated with both Vbeam and Cynergy. Patients underwent three treatment sessions. Treatment parameters used were as follows: (1) Cynergy® , Cynosure Corp, 595 nm wavelength, radiant exposure of 11 J/cm2 , 2 ms pulse duration, 7 mm spot size, cold-air cooling system of level three. (2) Vbeam® , Candela Corp, 595 nm wavelength, radiant exposure of 11 J/cm2 , 1.5 ms pulse duration, 7 mm spot size, cryogen spray cooling (30 ms of cooling with a 20 ms delay). Clinical efficacy outcomes were Uggs For Men evaluated by chromameter and Ugg Sko Salg visual assessment two months posttreatment.RESULTS: All patients were treated by both Vbeam and Cynergy on adjacent sites. Chromameter evaluation showed that the average blanching rate was 21.24% for Cynergy sites and 36.42% for Vbeam sites. This difference was statistically significant (p = 0.05), which suggests that PWS respond better to Vbeam compared with Cynergy at the settings used in this study. No patients developed scarring or permanent pigmentation change.CONCLUSION: Compared with Cynergy, Vbeam may be more effective in PWS treatment. Despite using supposedly equivalent fluences in 595 nm PDLs, one cannot guarantee equivalent clinical results. This article is protected by copyright. All rights reserved.This article is protected by copyright. All rights reserved.  




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